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Chemotherapy for Mesothelioma
1) To minimize the tumor before surgery
2) To kill remaining cancer cells after surgery
3) To kill cancer tumor that recurs
4) To use on patients who are not surgical candidates.
Chemotherapy is being continually developed by the researchers. Good news for the mesothelioma patients is that, there is considerable progress is the systematic treatment of this disease in last few years. Pemetrexed is seen as the most promising drug to treat mesothelioma. This is an inhibitor of proteins including thymidylate synthase and dihydrofolate reductase which are required in synthesis of DNA.
Chemotherapy drugs are often used in combination of others and this process is called combination therapy. When cancer occurs, bad cells in the body keep growing as exponential rate and the anticancer drugs can help the bad cells keep in control and during the process good cells may also get damaged which is the main reason for side effects. The cells most likely to be affected are the fast-growing normal cells such as the blood cells forming in bone marrow, and cells in the digestive tract which includes the mouth, stomach, intestines, and esophagus. Hair follicles may also be affected, hence, hair loss during chemotherapy. Some drugs affect cells of vital organs, such as the heart, kidney, bladder, lungs, and nervous system.
Mesothelioma Prognosis
Peritoneal mesothelioma has multiple stages. Pleural and peritoneal types of mesothelioma are very hard to be treated. They would ultimately be diagnosed at an advanced state and the statistics show that there are very few survivors. There are lot of contradictions among the studies whether peritoneal mesothelioma or pleural mesothelioma is more deadlier than other but one thing which cannot be contradicted is they both are difficult to treat as there is no proper treatment.
Only 10% of all who are diagnosed with mesothelioma live 3 years or more and only 5% of those go beyond 5 years, which shows the deadly nature of the disease. Only in people where mesothelioma is diagnosed in the early states, the survival rate goes till 50% for who lived more than three years. This was a study conducted on more than 200 people of mesothelioma affected people.
There was a broad study conducted in Europe on 5 million people and the outcome of that research is nothing different as only 25 % of people with pleural mesothelioma and 35% with peritoneal mesothelioma survived more than 10 months after study.
The overall health of the patient could also determine the prognosis of the patient. The healthier the higher chances for more days of survival. However, patients should not get disheartened as the statistics represent only the past but the future could be bright and different.
Compensation for Mesothelioma sufferers
Since there will be long latency for the asbestos related cancer, the employees will not know whether they developed mesothelioma until 20 to 30 years. Once they start observing the symptoms they go to the doctors and finally they discover that they developed mesothelioma cancer as a result of their work which involved asbestos. This would come as a total surprise to so many victims.
The compensation the mesothelioma sufferers get will make them eligible to file for is to cover all the medical expenses which this bloody disease can incur not more than the suffering, pain the victims go through. Another way to look at the compensation is to help the dependants of the victim if he is severely disabled. Four to twelve months is the typical survival rate of a mesothelioma patient.
You must act swiftly to file your claim for compensation. A lot of effort is required to put a solid case or build a solid case and there are certain time limits within which action has to be taken. According to the state laws, the attorney can suggest what to do to hasten the process. The amount the victims get from such cases depends on a number of factors. If your case is very strong, he may try to get a out of the court settlement which saves you lot of time instead of dragging the case in the court for years. The compensation depends on how badly you are affected by the asbestos exposure. Many people claim millions securing the futures of their families and also covering the pain and expenses of mesothelioma treatment. Time is important if you are planning to file a lawsuit on mesothelioma and you should do it as early as possible.
Story of Mesothelioma survivor
He stopped talking any medication and he believed running will help him his condition as he got to know it from a fellow sufferer. So he went running day in and day out to prove the doctors wrong who had not much hope to cure the cancer. He is proactive in treating his disease and has participated in several meso races to raise awareness and funding.
Inspite of all this, it is very surprising that asbestos is not banned in United States. This material is still used in various manufacturing industries and particularly construction industry, There was a bill to ban asbestos in 1989 and the Washington senators almost got it passes but the judge overturned it. However, Europe countries have banned the use of asbestos in mid 2005.
There is a lot of medical research going on with treating mesothelioma however the current measures are very ineffective. The reason for him to run is to raise funds for the research so he was kind of great in helping not only him but every sufferer of mesothelioma.
Mesothelioma treatment and settlement help
You should immediately consult your preferred doctor for diagnosis and early treatment improves the outcome. Tumors which are often hard to get rid of can be removed surgically if they have not yet metastasized. Radiation is another option as a treatment and chemotherapy treatment for mesothelioma is also recommended which will help in slow the growth of cancer. Oncologists are usually recommended by your primary physicians. Even after the treatment, statistics tells us that the survival rate is not impressive but all hope is not lost as there are many people who responded well to the treatment and are living healthier now.
There are a lot of advertisements on the television about this disease that offer legal advice on mesothelioma which will make people wonder if they need attorney when they develop this disease. Legal assistance is required if you want to make a settlement for your case. Legal assistance is always helpful and is free for initial consultations in most cases. Attorney can help people to find where they have significant asbestos exposure and will help you sue the companies that landed you in your situation. They can also help in getting supplemental security income or disability but you might have to pay for this service.
A successful lawsuit can pay for your health care which many time may not be covered in your insurance or could be used to support the dependants of the victim. It will take several years to win mesothelioma lawsuits so patience is required. It is important to look for a lawyer in this area and enquire about the percentage wins.
How do I choose a mesothelioma attorney to file lawsuits?
If you come across other people who have had gone through the mesothelioma lawsuit successfully, ask about their experience and also about their attorney. If you get positive feedback, he could be the person who can go with. If you have suffered asbestos exposure many years ago, you may not come across people who got affected by asbestos.
In such cases, find all your local attorney listings either from internet or any such resource. Call into each attorney and schedule a free consultation. Ask the attorney specific questions related to their experience in dealing with mesothelioma lawsuit cases. Also find if they successfully handled the asbestos exposure cases to get money for their clients.
Pay attention to the details the attorney discusses with you. Make sure your attorney understands your complications and find an attorney with patience. Patience is highly required in dealing such cases. Also talk about the payment arrangements beforehand. Most attorneys accept to handle the case and take money only if they win the asbestos exposure case for you.
Also check the mesothelioma attorney directory.
Mesothelioma settlement and mesothelioma claims
Mesothelioma is a cancer which develops in lung cancer and spreads to other parts. This is very difficult to treat. Asbestosis on the other hand is a chronic respiratory disease which can impair your lung functionality. People who develop one or the other can pursue an asbestosis or mesothelioma settlement.
If you are planning to seek a mesothelioma settlement, you should first locate an attorney who can deal your case. I will explain in other post how to find an attorney for mesothelioma settlement cases. As with any other cases, it is important to find an attorney who has experience in dealing such cases. Once you find an attorney with whom you are comfortable with, you have to build your case.
Many factors influence your case such as a when and where you were exposed to asbestos. Is it a work or home location? Were you aware of it at that time or for the matter has your employer made you aware? You have to build your case in such a way that(only if you want to win), you should prove that you are exposed to asbestos at work location only because of your employer’s negligence.
There are two ways to make your mesothelioma settlement. One is you go to the court along with defendant and the outcome will be determined by the jury. The other is out of the court settlement so your employer will pay you money. Your attorney will be able to advice you which route you should take.
Asbestos
Asbestos is the name for a mineral grouping that occurs naturally in nature. It has been widely used, particularly in construction. The fibrous bundles of asbestos are separated to produce thin and durable sheets. The reason why this material has come to be so widely used in various industries is because its fibers have a resistance to heat, fire and chemicals, and it is not a conductor of electricity.
Although the use of asbestos may appear to be practical and harmless, evidence has shown that those exposed to asbestos, whether at home or at the workplace, face a severe health risk. Any disturbance to asbestos products can cause the release of asbestos fibers into the air that may then be breathed in. This can be extremely serious, as when breathed in, the particles could get trapped and remain lodged in the lungs for a long time. The accumulation of these fibers over time causes inflammation and scarring, affecting the respiratory function and can result in severe health problems.
The fact that asbestos has been classified as a human carcinogen should give you a clear idea of the risk it poses. Exposure to asbestos increases the likelihood of developing pleural plaques, pleural thickening, and benign pleural effusions, lung cancer and mesothelioma. Asbestosis is in fact the term for the condition resulting from exposure to asbestos and indicates the presence of symptoms like chest pain, breathing difficulties, scarring, stabbing pains, and other permanent lung damage that increases the risk of the fore mentioned diseases.
There are various factors that can add up to increase the risk posed to you from asbestos exposure.
· The source
· The dosage exposed to
· The duration of the exposure
· The nature of the asbestos fibers or manufacturing process – size, shape and chemical makeup
· Individual considerations such as the presence of a pre-existing lung disease or smoking
The risk of course, increases with heavier and more prolonged exposure, but can also be serious when only brief. Keep in mind that the signs of illness may not surface until long after the initial exposure.
Mesothelioma: Simple Questions and Answers
Mesothelioma is a rare form of cancer in which malignant (cancerous) cells are found in the mesothelium, a protective sac that covers most of the body’s internal organs. Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles.
- What is the mesothelium? The mesothelium is a membrane that covers and protects most of the internal organs of the body. It is composed of two layers of cells: One layer immediately surrounds the organ; the other forms a sac around it. The mesothelium produces a lubricating fluid that is released between these layers, allowing moving organs (such as the beating heart and the expanding and contracting lungs) to glide easily against adjacent structures.The mesothelium has different names, depending on its location in the body. The peritoneum is the mesothelial tissue that covers most of the organs in the abdominal cavity. The pleura is the membrane that surrounds the lungs and lines the wall of the chest cavity. The pericardium covers and protects the heart. The mesothelial tissue surrounding the male internal reproductive organs is called the tunica vaginalis testis. The tunica serosa uteri covers the internal reproductive organs in women.
- What is mesothelioma? Mesothelioma (cancer of the mesothelium) is a disease in which cells of the mesothelium become abnormal and divide without control or order. They can invade and damage nearby tissues and organs. Cancer cells can also metastasize (spread) from their original site to other parts of the body. Most cases of mesothelioma begin in the pleura or peritoneum…..
- How common is mesothelioma? Although reported incidence rates have increased in the past 20 years, mesothelioma is still a relatively rare cancer. About 2,000 new cases of mesothelioma are diagnosed in the United States each year. Mesothelioma occurs more often in men than in women and risk increases with age, but this disease can appear in either men or women at any age.
- What are the risk factors for mesothelioma? Working with asbestos is the major risk factor for mesothelioma. A history of asbestos exposure at work is reported in about 70 percent to 80 percent of all cases. However, mesothelioma has been reported in some individuals without any known exposure to asbestos.Asbestos is the name of a group of minerals that occur naturally as masses of strong, flexible fibers that can be separated into thin threads and woven. Asbestos has been widely used in many industrial products, including cement, brake linings, roof shingles, flooring products, textiles, and insulation. If tiny asbestos particles float in the air, especially during the manufacturing process, they may be inhaled or swallowed, and can cause serious health problems. In addition to mesothelioma, exposure to asbestos increases the risk of lung cancer, asbestosis (a noncancerous, chronic lung ailment), and other cancers, such as those of the larynx and kidney.Smoking does not appear to increase the risk of mesothelioma. However, the combination of smoking and asbestos exposure significantly increases a person’s risk of developing cancer of the air passageways in the lung.
- Who is at increased risk for developing mesothelioma? Asbestos has been mined and used commercially since the late 1800s. Its use greatly increased during World War II. Since the early 1940s, millions of American workers have been exposed to asbestos dust. Initially, the risks associated with asbestos exposure were not known. However, an increased risk of developing mesothelioma was later found among shipyard workers, people who work in asbestos mines and mills, producers of asbestos products, workers in the heating and construction industries, and other tradespeople. Today, the U.S. Occupational Safety and Health Administration (OSHA) sets limits for acceptable levels of asbestos exposure in the workplace. People who work with asbestos wear personal protective equipment to lower their risk of exposure.The risk of asbestos-related disease increases with heavier exposure to asbestos and longer exposure time. However, some individuals with only brief exposures have developed mesothelioma. On the other hand, not all workers who are heavily exposed develop asbestos-related diseases.There is some evidence that family members and others living with asbestos workers have an increased risk of developing mesothelioma, and possibly other asbestos-related diseases. This risk may be the result of exposure to asbestos dust brought home on the clothing and hair of asbestos workers. To reduce the chance of exposing family members to asbestos fibers, asbestos workers are usually required to shower and change their clothing before leaving the workplace.
- What are the symptoms of mesothelioma? Symptoms of mesothelioma may not appear until 30 to 50 years after exposure to asbestos. Shortness of breath and pain in the chest due to an accumulation of fluid in the pleura are often symptoms of pleural mesothelioma. Symptoms of peritoneal mesothelioma include weight loss and abdominal pain and swelling due to a buildup of fluid in the abdomen. Other symptoms of peritoneal mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever. If the cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face.These symptoms may be caused by mesothelioma or by other, less serious conditions. It is important to see a doctor about any of these symptoms. Only a doctor can make a diagnosis.
- How is mesothelioma diagnosed? Diagnosing mesothelioma is often difficult, because the symptoms are similar to those of a number of other conditions. Diagnosis begins with a review of the patient’s medical history, including any history of asbestos exposure. A complete physical examination may be performed, including x-rays of the chest or abdomen and lung function tests. A CT (or CAT) scan or an MRI may also be useful. A CT scan is a series of detailed pictures of areas inside the body created by a computer linked to an x-ray machine. In an MRI, a powerful magnet linked to a computer is used to make detailed pictures of areas inside the body. These pictures are viewed on a monitor and can also be printed.A biopsy is needed to confirm a diagnosis of mesothelioma. In a biopsy, a surgeon or a medical oncologist (a doctor who specializes in diagnosing and treating cancer) removes a sample of tissue for examination under a microscope by a pathologist. A biopsy may be done in different ways, depending on where the abnormal area is located. If the cancer is in the chest, the doctor may perform a thoracoscopy. In this procedure, the doctor makes a small cut through the chest wall and puts a thin, lighted tube called a thoracoscope into the chest between two ribs. Thoracoscopy allows the doctor to look inside the chest and obtain tissue samples. If the cancer is in the abdomen, the doctor may perform a peritoneoscopy. To obtain tissue for examination, the doctor makes a small opening in the abdomen and inserts a special instrument called a peritoneoscope into the abdominal cavity. If these procedures do not yield enough tissue, more extensive diagnostic surgery may be necessary.If the diagnosis is mesothelioma, the doctor will want to learn the stage (or extent) of the disease. Staging involves more tests in a careful attempt to find out whether the cancer has spread and, if so, to which parts of the body. Knowing the stage of the disease helps the doctor plan treatment.
Mesothelioma is described as localized if the cancer is found only on the membrane surface where it originated. It is classified as advanced if it has spread beyond the original membrane surface to other parts of the body, such as the lymph nodes, lungs, chest wall, or abdominal organs.
- How is mesothelioma treated? Treatment for mesothelioma depends on the location of the cancer, the stage of the disease, and the patient’s age and general health. Standard treatment options include surgery, radiation therapy, and chemotherapy. Sometimes, these treatments are combined.
- Surgery is a common treatment for mesothelioma. The doctor may remove part of the lining of the chest or abdomen and some of the tissue around it. For cancer of the pleura (pleural mesothelioma), a lung may be removed in an operation called a pneumonectomy. Sometimes part of the diaphragm, the muscle below the lungs that helps with breathing, is also removed.
- Radiation therapy, also called radiotherapy, involves the use of high-energy rays to kill cancer cells and shrink tumors. Radiation therapy affects the cancer cells only in the treated area. The radiation may come from a machine (external radiation) or from putting materials that produce radiation through thin plastic tubes into the area where the cancer cells are found (internal radiation therapy).
- Chemotherapy is the use of anticancer drugs to kill cancer cells throughout the body. Most drugs used to treat mesothelioma are given by injection into a vein (intravenous, or IV). Doctors are also studying the effectiveness of putting chemotherapy directly into the chest or abdomen (intracavitary chemotherapy).
To relieve symptoms and control pain, the doctor may use a needle or a thin tube to drain fluid that has built up in the chest or abdomen. The procedure for removing fluid from the chest is called thoracentesis. Removal of fluid from the abdomen is called paracentesis. Drugs may be given through a tube in the chest to prevent more fluid from accumulating. Radiation therapy and surgery may also be helpful in relieving symptoms.
- Are new treatments for mesothelioma being studied? Yes. Because mesothelioma is very hard to control, the National Cancer Institute (NCI) is sponsoring clinical trials (research studies with people) that are designed to find new treatments and better ways to use current treatments. Before any new treatment can be recommended for general use, doctors conduct clinical trials to find out whether the treatment is safe for patients and effective against the disease. Participation in clinical trials is an important treatment option for many patients with mesothelioma.People interested in taking part in a clinical trial should talk with their doctor. Information about clinical trials is available from the Cancer Information Service (CIS) (see below) at 1–800–4–CANCER. Information specialists at the CIS use PDQ®, NCI’s cancer information database, to identify and provide detailed information about specific ongoing clinical trials. Patients also have the option of searching for clinical trials on their own. The clinical trials page on the NCI’s Cancer.gov Web site, located at http://www.cancer.gov/clinicaltrials on the Internet, provides general information about clinical trials and links to PDQ.People considering clinical trials may be interested in the NCI booklet Taking Part in Cancer Treatment Research Studies. This booklet describes how research studies are carried out and explains their possible benefits and risks. The booklet is available by calling the CIS, or from the NCI Publications Locator Web site at http://www.cancer.gov/publications on the Internet.
What are the different types of mesothelioma?
The symptoms occur in the abdomen and spreads to other organs like spleen or bowel. It causes severe discomfort in the abdomen. Other symptoms of peritoneal mesothelioma may include difficult bowel movements, nausea and vomiting, fever and swollen feet.
The survival rate is even worse for those diagnosed with peritoneal mesothelioma will patients typically surviving only ten months from time that they first started experiencing the symptoms noted above.
2) Malignant Mesothelioma
This is the cancer that is caused because of asbestos and is most serious and often the symptoms are hard to diagnose. Malignant mesothelioma is diagnosed, it will be in severe stage and patients may not respond well to the treatment by the doctors.
3) Pericardial Mesothelioma
This is the least common form. This involves the heart and as the disease spreads, the heart will not be able to deliver oxygen to the body which in turn causes further bad health. Symptoms are pain in the chest and shortness of breath.
4) Pleural Mesothelioma
This affects the chests and lungs and is not always detectable. This form of mesothelioma can affect lot of organs including brain. The survival rate for patients diagnosed with pleural mesothelioma typically is not high. Patients typically do not live beyond seventeen months from the onset of symptoms. Only 8% of those diagnosed with mesothelioma will live three to five years from the onset of symptoms.
5) Benign Mesothelioma
This affects the peritoneum. This is also extremely difficult to diagnose and requires specialized microscopes and immunologic techniques to aid in diagnosis.
2009 International Symposium on Malignant Mesothelioma
The 2009 International Symposium on Malignant Mesothelioma will take place this June in Washington, DC. Organized by the Mesothelioma Applied Research Foundation (Meso Foundation), the event will feature international specialists as well as mesothelioma patients, caregivers, and advocates.
Leading international experts in the asbestos-related cancer, mesothelioma, will join mesothelioma patients, caregivers, loved ones and advocates to share the latest in treatment, research and clinical trials at the International Symposium on Malignant Mesothelioma. The event starts on Thursday, June 25th and runs through Saturday June 27th at the Omni Shoreham Hotel, in Washington, DC.
The Symposium, organized annually by the Mesothelioma Applied Research Foundation (Meso Foundation) will highlight the latest advances in mesothelioma research and treatment for patients and caregivers, offer psychosocial support to them and those who have lost loved ones to the disease, and provide all who are intent on helping to find a cure for mesothelioma with significant advocacy and volunteer opportunities.
Sessions during the three-day conference will feature worldwide mesothelioma experts discussing the most current developments in research, treatments and projected initiatives. Science Day also provides the lay participants with the opportunity to interact informally and extensively with the experts. More information about the sessions is on the Meso Foundation’s website.
At the Gala Dinner Friday evening, the Meso Foundation and the community will honor patients living with mesothelioma, and give the Foundation’s traditional three annual awards. The Bruce Vento Hope Builder Award, named for the late Minnesota Congressman who died from mesothelioma in 2000, acknowledges the support and initiatives of a political leader. The Pioneer Award highlights the contribution made by a researcher or company toward new mesothelioma treatment options. And the Volunteer of the Year Award honors the efforts of the members of the community.
Friday morning includes a tribute ceremony for the community to remember and acknowledge those who have been lost to mesothelioma. All those who have lost a loved one to the disease are invited to submit their loved one’s name and photograph and participate in this special ceremony.
The Mesothelioma Applied Research Foundation is the national non-profit dedicated to finding a cure for mesothelioma by funding mesothelioma research, providing mesothelioma patients support services and participating in federal mesothelioma advocacy.
To register for the symposium or for additional information, please visit the Meso Foundation’s website at http://www.curemeso.org.
CDC’s Morbidity and Mortality Weekly Report Analyzes Mesothelioma Death Rates
Cause of death records from the NIOSH’s NORMS database show the number of malignant mesothelioma deaths rose from 2,482 in 1999 to 2,704 in 2005. A 2004 article from the American Journal of Epidemiology cited by the MMWR report suggests the diagnosis of mesothelioma may peak in 20101.
These increases, despite the sharp decline in asbestos usage since importation of the mineral peaked in 1973, are a result of the long latency period between asbestos exposure and disease progression. Asbestos-related diseases often develop 20, 30, or 40 years after the initial exposure.
However, the MMWR report cautions against complacency. Asbestos is not banned; some 1700 metric tons were imported into the US in 2007.
While this is a far cry from the more than 800,000 metric tons imported annually at the height of asbestos use, this "new" asbestos combined with the substantial amounts of already present in buildings makes asbestos exposure a concerning risk even today. According to OSHA’s estimates, "1.3 million construction and general industry workers potentially are being exposed to asbestos."
Even if the number of new mesothelioma cases begins to decline in 2010, it will be years before the effects of decades of poor asbestos management and lackluster concern for worker safety are no longer apparent in the statistics.
Of the 18,068 deaths between 1999-2005 which were analyzed:
* 80% were men
* 95% were white
The six states with the highest rate of death attributable to mesothelioma were:
* Maine (22.2 per million residents)
* Wyoming (22.2 per million residents)
* West Virginia (21.0 per million residents)
* Pennsylvania (20.8 per million residents)
* New Jersey (20.2 per million residents)
* Washington (20.1 per million residents)
Which occupations are at risk from Mesothelioma Disease
- Aerospace and missile production workers
- Aircraft manufacturing production workers
- Aircraft mechanics
- Asbestos textile mill workers
- Automobile manufacturing production workers, including automobile mechanics and brake repairers
- Boilermakers
- Brake and clutch manufacturing and assembly workers
- Building engineers
- Building material products manufacturers
- Cement plant production workers
- Coast guardsmen
- Construction workers, including insulators, boilermakers, laborers, steel/ironworkers, plumbers, steam fitters, plasterers, drywallers, cement and masonry workers, roofers, tile/linoleum installers, carpenters, HVAC mechanics and welders
- Custodians
- Demolition and wrecking crews
- Electrical workers, including electricians, electrical and telephone linemen
- Family members of occupationally exposed people
- Insulation manufacturing plant workers
- Insulators
- Longshoremen
- Machinists
- Merchant mariners
- Packing and gasket manufacturing plant workers
- Pipefitters
- Powerhouse workers, including insulators and pipefitters
- Protective clothing and glove makers
- Railroad workers, including locomotive mechanics, car mechanics and rebuilders, and maintenance personnel
- Refinery workers, including insulators and pipefitters
- Refractory products plant workers
- Rubber workers, including tire makers and hose makers
- Sheetmetal workers
- Shipyard workers, including electricians, insulators, laborers, laggers, painters, pipefitters, maintenance workers and welders
- Steamfitters
- U.S. Navy personnel
- Warehouse workers
PAIN MANAGEMENT
Mesothelioma patients often suffer from a great deal of pain as a result of their illness. Tumors can press on nerves, organs or bones causing pain ranging from mild to severe. There can also be pain associated with the mesothelioma treatment itself - whether treatment is from surgery, chemotherapy or radiation. Psychological pain associated with the knowledge that you have cancer or the belief that the demands of cancer are burdensome to family and friends can be difficult, as well.
The three most common types of pain are chronic, acute and breakthrough. Chronic pain can be varying in degree from mild to severe and persists over a long time. Acute pain is short in duration, quite sudden and severe. Someone who experiences pain when his or her chronic pain is normally controlled by medication is said to have "breakthrough" pain.
Many patients are unaware of the numerous resources available that can help them feel better - some of them at no cost. There is no benefit to enduring this pain as it can cause problems sleeping, problems with activity and movement, make a patient less likely to eat, increase depression, and interfere with how a patient interacts with family and friends. Untreated, pain can diminish a patient’s quality of life.
Management Bay Objective ( MBO )
K. Management Bay Objective ( MBO )
Pertama kali diperkenalkan oleh Peter Drucker dalam bukunya The Practice of Management pada tahun 1954. Management by objective dapat juga disebut sebagai manajemen berdasarkan sasaran, manajemen berdasarkan hasil (Management by Result), Goals management, Work planning and review dan lain sebagainya yang pada intinya sama.
Management by objective menekankan pada pentingnya peranan tujuan dalam perencanaan yang efektif, dengan menetapkan prosedur pencapaian baik yang formal maupun informal, pertama dengan menetapkan tujuan yang akan dicapai dilanjutkan dengan kegiatan yang akan dilaksanakan sampai selesai baru diadakan peninjauan kembali atas pekerjaan yang telah dilakukan. Kegiatan MBO singkatan dari management by objective yaitu proses partisipasi yang melibatkan bawahan dan para manajer dalam setiap tingkatan organisasi yang dirumuskan dengan bentuk misi atau sasaran, yang dapat diukur dimana penggunaan ukuran ini sebagai pedoman bagi pengoperasian satuan kerja.
L. Sistem Management By Objective Yang Efektif
1. Adanya komitmen para manajer tujuan pribadi dan organisasi, sehingga dia harus berjumpa dengan bawahannya untuk memberikan penetapan tujuan dan menilainya.
2. Penetapan tujuan manajemen puncak yang dinyatakan dalam nilai tertentu yang dapat diukur, sehingga antara manajer dan bawahan mempunyai gagasan yang jelas tentang apa yang diharapkan oleh manajemen puncak, sehingga dapat diketahui antara individu dengan tujuan organisasi secara keseluruhan.
3. Tujuan perseorangan, dimana antara manajer dan bawahan harus merumuskan tujuan bersama dan tanggung jawab terhadap bagiannya secara jelas guna memahami tentang apa yang akan dicapai.
4. Perlunya partisipasi semua pihak, dimana semakin besar partisipasi dari semua anggota, maka semakin besar tujuan yang akan tercapai.
5. Otonomi dan implementasi rencana, disini bawahan dan manajer bebas untuk mengembangkan dan mengimplementasikan program-program pencapaian tujuannya.
6. Peninjauan kembali prestasi yang dilakukan secara periodik terhadap kemajuan tujuan.
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Jackson lahir pada 29 Agustus 1958 di Gary,
Jackson lahir pada 29 Agustus 1958 di Gary, Indiana, dan merupakan anak ketujuh dari sembilan bersaudara dan pertamakali tempil bersama empat abangnya dalam Jackson 5.Albumnya pada 1982 “Thriller” berhasil menempatkan tujuh lagunya sekaligus dalam barisan 10 lagu terpopuler pada tangga lagu dunia. Album ini terjual 21 juta kopi di AS dan kira-kira 27 juta secara internasional.chord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalahjackson
Jackson lahir pada 29 Agustus 1958 di Gary,
Jackson lahir pada 29 Agustus 1958 di Gary, Indiana, dan merupakan anak ketujuh dari sembilan bersaudara dan pertamakali tempil bersama empat abangnya dalam Jackson 5.Albumnya pada 1982 “Thriller” berhasil menempatkan tujuh lagunya sekaligus dalam barisan 10 lagu terpopuler pada tangga lagu dunia. Album ini terjual 21 juta kopi di AS dan kira-kira 27 juta secara internasional.chord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalahjackson
Meskipun ada laporan Jackson menderita sakit, promotor pentas di London, AEG Live, Maret, mengatakan bahwa Jackson telah melewati uji kesehatan fisik
Jackson dua kali dituduh menganiaya dua bocah laki-laki dan didakwa telah melakukan kekerasan seksual terhadap anak pada 2003. Dia menjadi makin tertu
Namun reputasi Jackson sebagai penyanyi dan penari beberapa tahun belakangan dibayangi oleh penampilannya yang abnormal dengan gaya hidup yang ganjil, diantaranya kedekatannya dengan seekor simpanse (monyet) dan menganggap dirinya pelindung anak-anak.Dia menamai komplek rumah mewahnya di kaki bukit di California tengah “Neverland Valley Ranch” yang diambil dari kisah Peter Pan karya J.M. Barrie, dan memenuhinya dengan taman bermain dan kebun binatang mini.
Jackson dua kali dituduh menganiaya dua bocah laki-laki dan didakwa telah melakukan kekerasan seksual terhadap anak pada 2003. Dia menjadi makin tertutup setelah pembebasannya dari tuduhan pengadilan pada 2005 dan bersumpah tidak akan lagi tinnggal di Neverland.
Di tengah reputasi yang memburuk dan belitan utang menggunung yang dilaporkan Wall Street Journal mencapai 500 juta dolar AS, Jackson menghabiskan waktu dua bulan terakhir untuk berlatih menghadapi konser di London, termasuk konser Rabu malam di stadion besar di Staples Center, markas klub bola basket Los Angeles Lakers.Michord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalahchord adsense ga jelas tab makalah
hol atau resep obat pada sistem tubuhnya.
Para detektif dari Bagian Perampokan dan Pembunuhan, Kepolisian Los Angeles menggeledah rumah Jackson di Perumahan Holmby Hills di kawasan kota Los Angeles, atas perintah Inspektur William Bratton.Namun para penyelidik mengaku investigasi ini adalah hal rutin yang biasa mereka lakukan ketika terjadi peristiwa seperti itu.Misteri kematian michael
Konser di London dianggap sebagai simbol kembalinya Jackson yang mendominasi dunia pop selama 1980an melalui album seperti “Thriller” dan “Billie Jean” dan dihormati karena mengubah video musik menjadi bentuk seni mahal bercita rasa tinggi.Dia dianggap sebagai salah seorang entertainer paling sukses di abad lalu, dengan penjualan album terbesar sepanjang masa 750 juta kopi dan mendapatkan 13 Grammy.
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“Perawatan kesehatan padanya
Hanya didapat sekelumit k
Brian Oxman, juru
Sehari setelah kematian
Tanggung Jawab Soal Manajer
Perubahan konsep manajerial dipengaruhi oleh faktor intern dan ekstern. Seorang manajer mempunyai tanggung jawab social atas keputusan-keputusan yang diambil, mengapa dikatakan demikian karena mempengaruhi dalam pencapaian tujuan organisasi baik dalam jangka panjang maupun dalam jangka panjang, disamping itu juga menyangkut hajat hidup orang banyak yang
Perubahan konsep manajerial dipengaruhi oleh faktor intern dan ekstern. Seorang manajer mempunyai tanggung jawab social atas keputusan-keputusan yang diambil, mengapa dikatakan demikian karena mempengaruhi dalam pencapaian tujuan organisasi baik dalam jangka panjang maupun dalam jangka panjang, disamping itu juga menyangkut hajat hidup orang banyak yang kesemuanya menggantungkan dirinya kepada organisasi tersebut (ini kalau dilihat dari segi dimana seseorang bekerja). Atas dasar ini maka seorang manajer dituntut untuk dapat mengimplementasikan etika berusaha (the ethics of manager). Ada lima faktor yang mempengaruhi keputusan manajer dalam etika berusaha ini, yaitu hukum; peraturan-peraturan pemerintah termasuk di dalamnya undang-undang yang dikeluarkan oleh pemerintah; kode etik industri dan perusahaan tekanan-tekanan sosial; tegangan antar standar perorangan dan kebutuhan organisasi
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Organisasi Dan Lingkungan
Setiap manajer dipengaruhi oleh faktor-faktor lingkungan eksternal dalam pengambilan keputusan. Keputusan yang diambil tergantung pada bentuk dan tujuan yang akan dicapai oleh organisasi, disamping itu keputusan juga dipengaruhi oleh dimana seorang manajer duduk dalam posisinya.
Manajer dan organisasi memberikan tanggapan terhadap lingkungan eksternal, baik melalui pengaruh lingkungan yang bersifat mikro, prediksi maupun lingkungan yang bersifat makro, disamping itu juga bisa melalui perencanaan, perancangan organisasi dan lingkungan itu sendiri.
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B. Faktor Lingkungan Eksternal
Lingkungan ekstern atau eksternal terdiri atas unsur-unsur yang berada di luar organisasi, dimana unsur-unsur ini tidak dapat dikendalikan dan diketahui terlebih dahulu oleh manajer, disamping itu juga akan mempengaruhi manajer di dalam pengambilan keputusan yang akan dibuat. Unsur-unsur lingkungan eksternal organisasi contohnya yaitu perubahan perekonomian, peraturan pemerintah, perilaku konsumen atau masyarakat, perkembangan teknologi, politik dan lain sebagainya.
Lingkungan eksternal dibagi menjadi dua yaitu lingkungan mikro dan lingkungan makro. 1. Lingkungan eksternal mikro yaitu lingkungan yang mempunyai pengaruh langsung terhadap kegiatan manajemen. Lingkungan eksternal makro yaitu lingkungan yang mempunyai pengaruh tidak langsung.
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A Closer Look at Mesothelioma and Michigan Lawyers
Mesothelioma was one of the most rare forms of cancer. However, with the growing number of patients diagnosed as having mesothelioma, one can't call it rare, even though it still remains uncommon. Mesothelioma is affecting the cells of the mesothelium - found in the chest - whereby they become aberrant and they multiply without order or control. The aberrant or cancer cells can attack and damage nearby organs and tissues, and they can also metastasize or spread from where they originally were to other parts of the body. Yearly, a giant number of mesothelioma cases are diagnosed in Michigan. Men are found to be more at the mercy of mesothelioma, also often referred to as asbestosis, than ladies. This could be due to higher risk factors that men face. The danger also increases as one gets older. However, anybody - woman or man - can develop mesothelioma at any age.
Cancers in the mesothelium can be benign or non-cancerous. Or they may also be malignant or cancerous. Noxious mesothelioma is discovered to be the most significant of all asbestos-related illnesses. The sole known reason for mesothelioma is exposure to the fatal mineral that we think we know as asbestos.As have been discussed, any one can become troubled with mesothelioma at any age but almost all of the time, patients begin to fall ill only after 20 to 30 years. Mesothelioma patients regularly whinge about trouble breathing and agony felt in the chest. The chest agony is commonly because of the accumulation of liquid in the pleura. Patients might also observe weight reduction and experience intestinal discomfort.Some swelling could also be observed due to liquid buildup in the stomach. Patients could also have bowel obstruction, abnormalities in blood clotting, fever, and anemia. Once the cancer cells have spread outside the mesothelium, patients may moan of agony, trouble in swallowing, and swelling of the neck and / or face. It's been revealed that most mesothelioma patients have received exposure to threatening levels of asbestos in their work places. This has resulted to lots of mesothelioma legal actions filed in courts of law against culpable bosses.
Patients who face a mesothelioma diagnosis have a right to seek answers on why they weren't given alerts on the danger of asbestos exposure.
They also have a right to get reparations for themselves and their families. In Michigan, there are numerous mesothelioma barristers who can help mesothelioma patients. These barristers have the data, experience, and resources wanted to fight a fair battle against giant corporations who have shown failure for their workers. Michigan mesothelioma barristers do all they're able to to help mesothelioma patients and their families to claim fair and just recompense for the agony and difficulty caused by asbestosis exposure.
